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INDIANAPOLIS, Sept. 20, 2020 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced Verzenio(®) (abemaciclib) in combination with standard adjuvant endocrine therapy (ET) significantly decreased the risk of breast cancer recurrence by 25 percent compared to standard adjuvant ET alone for people with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) high risk early breast cancer (HR: 0.747; 95% CI: 0.598, 0.932; p = 0.0096). This statistically significant benefit was consistent across all pre-specified subgroups and corresponds to a 3.5 percent difference between arms (92.2 percent in the Verzenio arm and 88.7 percent in the control arm) at two years. These results are from a preplanned interim analysis with 323 IDFS events observed in the intent-to-treat population across both arms, including 136 in the Verzenio arm and 187 in the control arm. The data were presented today in the Presidential Symposium at the European Society for Medical Oncology (ESMO) 2020 Virtual Congress and simultaneously published in the Journal of Clinical Oncology.

MEXICO CITY - Ultimo Guerrero is one of the biggest names in Mexican wrestling - a world-famous star known for his punishing moves, long black mullet and silver-capped front tooth. He has toured Asia, South America and Europe, won dozens of championship belts and can't walk down the street here without fans pestering him for autographs. But in the months since the coronavirus struck and ...

PHILADELPHIA - Dawn Pittman retired from teaching in 2013 after more than three decades. But Pittman has no plans to give up her passion - even in a pandemic. When Camden resumes in-person learning, possibly in January, she hopes to answer the call as a substitute. "I absolutely love teaching," said Pittman, 58, of Merchantville, New Jersey. Retired Philadelphia teacher Janice Richardson has ...

Since Justice Ruth Bader Ginsburg died Friday night, President Donald Trump has largely winnowed a list of dozens of potential replacements down to three front-runners: Appeals court judges Amy Coney Barrett, Barbara Lagoa and Amul Thapar. Barrett, Lagoa and Thapar all appeared on a long list of possible high-court picks that Trump updated earlier this month. And Barrett and Thapar were among ...