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INDIANAPOLIS, Sept. 20, 2020 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced Verzenio(®) (abemaciclib) in combination with standard adjuvant endocrine therapy (ET) significantly decreased the risk of breast cancer recurrence by 25 percent compared to standard adjuvant ET alone for people with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) high risk early breast cancer (HR: 0.747; 95% CI: 0.598, 0.932; p = 0.0096). This statistically significant benefit was consistent across all pre-specified subgroups and corresponds to a 3.5 percent difference between arms (92.2 percent in the Verzenio arm and 88.7 percent in the control arm) at two years. These results are from a preplanned interim analysis with 323 IDFS events observed in the intent-to-treat population across both arms, including 136 in the Verzenio arm and 187 in the control arm. The data were presented today in the Presidential Symposium at the European Society for Medical Oncology (ESMO) 2020 Virtual Congress and simultaneously published in the Journal of Clinical Oncology.

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INDIANAPOLIS, Sept. 18, 2020 /PRNewswire/ -- Eli Lilly and Company (NYSE:LLY) and Incyte (NASDAQ:INCY) announced today that the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion for baricitinib for the treatment of adult patients with moderate to severe atopic dermatitis (AD) who are candidates for systemic therapy.

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INDIANAPOLIS, Sept. 18, 2020 /PRNewswire/ -- A new study published by the RAND Corporation reveals that a large sample of employers and private insurers across 49 states and District of Columbia pay, on average, 247% of what Medicare pays for the same hospital services, including both facility and professional fees for inpatient and outpatient care. Researchers analyzed hospital claims data representing $33.8 billion from 2016-2018 for 3,112 hospitals located in every state except Maryland. They collected data from self-insured employers, six state all-payer claims databases, and health plans across the country. The findings illustrate a wide variation in hospital facility and professional prices for the commercially insured population. The report also identifies the top 10 most expensive health systems in each state and reports individual hospital prices alongside quality and safety measures.

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FORT WAYNE, Ind., Sept. 17, 2020 /PRNewswire/ -- Steel Dynamics, Inc. (NASDAQ/GS: STLD) today provided third quarter 2020 earnings guidance in the range of $0.42 to $0.46 per diluted share. Excluding the impact from the following, the company expects third quarter 2020 adjusted earnings to be in the range of $0.46 to $0.50 per diluted share:

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INDIANAPOLIS, Sept. 17, 2020 /PRNewswire/ -- An independent, nationwide analysis of voter rolls in 42 states has identified thousands of probable deceased and duplicate registrants, as well as cases of individuals credited for voting more than once. The Public Interest Legal Foundation (PILF) has launched the Safeguarding America's Votes and Elections (SAVE) Database as an analysis tool to track voter roll deficiencies and potential problem areas across America. Announced today, the groundbreaking findings in their national report indicates that the SAVE Database raises serious concerns over the integrity of states' voter files as election officials anticipate a surge in mail-in voting this fall.

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INDIANAPOLIS, Sept. 17, 2020 /PRNewswire/ -- FAST BioMedical, a late clinical-stage medical technology company, today announces establishing a Heart Failure Medical Advisory Board of world-recognized physicians, nurses and researchers. The Board will advise FAST's clinical development of measuring volume status to better treat heart failure patients. The board collectively has decades of experience in heart failure and cardiovascular patient care and have contributed to more than 1,300 peer-reviewed publications.

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INDIANAPOLIS, Sept. 17, 2020 /PRNewswire/ -- The Heritage Group (THG) announced today that Kip A. Frey, its Executive Vice President for New Ventures, has been named to the Global Corporate Venturing (GCV) Powerlist 2020. Published annually, the Powerlist recognizes the world's top 100 leaders of in-house venture capital groups, drawn from a universe of more than 2,000 corporations that invest in innovative start-ups as part of their corporate strategies.

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FORT WAYNE, Ind., Sept. 17, 2020 /PRNewswire/ -- Caregiver Homes, Seniorlink's intensive home-based care management program, today announced a pilot with Aging & In-Home Services of Northeast Indiana, focused on care collaboration and efficiency.

INDIANAPOLIS, Sept. 16, 2020 /PRNewswire/ -- Shelley Clayton, MSN, FNP-BC of Ageless Aesthetics wins "Top Aesthetic Nurse Practitioner", "Top Women in Aesthetic Medicine", "Top Women Business Owners" and "Top Women Injectors" in the Aesthetic Everything® 2020 Aesthetic and Cosmetic Medicine Awards. In addition, Ageless Aesthetics wins "Top Medical Spa Midwest", Abbie Bledsoe wins "Top Women in Aesthetic Medicine" and Ashley Grant wins "Top Aesthetician".

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INDIANAPOLIS, Sept. 16, 2020 /PRNewswire/ -- ADISA, the nation's largest trade association for the alternative and direct investment space, announced today the results of its co-sponsored study, The Tax and Economic Impacts of Section 1031 Like-Kind Exchanges in Real Estate, which concluded that the elimination of Section 1031 exchanges would disrupt many local property markets, harm both tenants and owners as well as hurt small investors.

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CARMEL, Ind., Sept. 16, 2020 /PRNewswire/ -- Medical education agency Avant Healthcare today announced that Arun Divakaruni, PhD, has been promoted to Chief Executive Officer. Dr. Divakaruni joined Avant Healthcare in 2019 as Chief Science Officer.

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MERRILLVILLE, Ind., Sept. 16, 2020 /PRNewswire/ -- NiSource Inc. (NYSE: NI) will host a virtual Investor Day on Tuesday, September 29, 2020. President and Chief Executive Officer Joe Hamrock, and other members of NiSource's senior management team, will discuss the company's long-term growth strategy. The two hour presentation will begin at 11:00 am ET and will be followed by a Q&A session.

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INDIANAPOLIS, Sept. 16, 2020 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced proof of concept data from an interim analysis of the BLAZE-1 clinical trial, showing a reduced rate of hospitalization for patients treated with LY-CoV555. The randomized, double-blind, placebo-controlled Phase 2 study evaluated LY-CoV555, a SARS-CoV-2 neutralizing antibody, for the treatment of symptomatic COVID-19 in the outpatient setting. The trial enrolled mild-to-moderate recently diagnosed COVID-19 patients across four groups (placebo, 700 mg, 2800 mg, and 7000 mg).

PHILADELPHIA - Dawn Pittman retired from teaching in 2013 after more than three decades. But Pittman has no plans to give up her passion - even in a pandemic. When Camden resumes in-person learning, possibly in January, she hopes to answer the call as a substitute. "I absolutely love teaching," said Pittman, 58, of Merchantville, New Jersey. Retired Philadelphia teacher Janice Richardson has ...

Since Justice Ruth Bader Ginsburg died Friday night, President Donald Trump has largely winnowed a list of dozens of potential replacements down to three front-runners: Appeals court judges Amy Coney Barrett, Barbara Lagoa and Amul Thapar. Barrett, Lagoa and Thapar all appeared on a long list of possible high-court picks that Trump updated earlier this month. And Barrett and Thapar were among ...

Vice presidential nominee Kamala Harris is expected to play a prominent role in the fight against President Donald Trump's Supreme Court nominee, though it's not clear whether she'll tear into the pick in the same way she went after now-Justice Brett Kavanaugh, an appearance that brought her to national prominence. During the Kavanaugh hearing, Harris was just one of 100 senators. Now she's ...

A second Republican senator said she won't support taking up a Supreme Court vacancy so close to the election, leaving Democrats to find two more to potentially put the brakes on President Donald Trump's effort to fill Justice Ruth Bader Ginsburg's seat. Sen. Lisa Murkowski of Alaska announced her position in a statement on Sunday, joining Sen. Susan Collins of Maine in saying the election is ...